{ "info": { "author": "Yunfei Wang", "author_email": "yfwang0405@gmail.com", "bugtrack_url": null, "classifiers": [ "Development Status :: 3 - Alpha", "Environment :: Console", "Intended Audience :: Developers", "License :: Free for non-commercial use", "License :: OSI Approved :: GNU General Public License (GPL)", "Operating System :: Unix", "Programming Language :: Python :: 2.7", "Topic :: Scientific/Engineering :: Bio-Informatics" ], "description": "CONTENTS AND COPYRIGHT\n\nThis package is used for maniputating genome annotation and seqeunce files, such as Bed, GenePred, BAM, Wiggle and BigWig formats. Users interested in this package should contact yfwang0405@gmail.com for details. This package uses the Vienna RNA Package lib and H directories (external/RNAlib/fold) and RNAStructure libs (external/RNAlib/plot), and users should read the COPYING or ReadMe.txt files inside and behave accordingly. All files are copyrighted, but license is hereby granted for personal, academic and non-profit use. Commercial users should contact yfwang0405@gmail.com.\n\nMANUALS\n\nhttp://rsqwiki.appspot.com\n\nSOURCES CODES\n\nhttps://pypi.python.org/pypi/rsq\n\nPREREQUISITES\n\n1. python 2.7, python-dev\n2. numpy >= 1.4.1 (automatically installed)\n3. ngslib >= 1.1.10 for NGS data processing (automatically installed)\n4. fisher >= 0.1.4 for fisher exact test ((automatically installed)\n4. sfold 2.2 stand-alone executable (http://sfold.wadsworth.org/License_info.html)\n\nGENERAL INSTALL INSTRUCTIONS\n\n1. Install from Python Package Index (https://pypi.python.org)\n > easy_install --prefix=$HOME/local rsq\n\n2. Install from source file (including the demo example files)\n >easy_install --editable --build-directory package_source/ rsq\n >cd package_source\n >python setup.py install --prefix=install_path\n\n3. sfold 2.2\n Download the stand-alone executable from http://sfold.wadsworth.org/License_info.html\n\tRun configure file\n\t >cd SFOLD2.2_HOME\n\t >./configure\n\tTest sfold in command line before use:\n\t >bin/sfold\n\tIf successful, add sfold binary file to system PATH by:\n\t PATH=$PATH:SFOLD2.2_HOME/bin/\n\t export PATH\n\nMAJOR MODULES\n\n- Data formats:\n\tFastD, FastC, FastS and EFastS to represent data used in RSQ.\n\n- IO:\n\tReaders for each data format\n\n- Predictor:\n\tWrappers of a series of RNA secondary structure prediction tools.\n\tRNAfold, mfold, UNAFold, sfold, et. al.\n\tNote: make sure the command/program is callable in shell before call it in RSQ.\n\n- Algorithm:\t\n\tEM algoritm, Boltzmann sampling, structure distance calculation, et. al.\n\n- Utils:\n\tUtilites. Temperature conversion, structure format conversion, et. al.\n\n- ThreadSafeFile:\n\tUsed in threading processing procedures.\n\nEXAMPLES\n\n\tExamples are in the examples folder.\n\t1. Dealing with genes without isoforms.\n\t2. Dealing with genes with multiple isoforms.\n\t3. 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