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        "author": "Martin Craig",
        "author_email": "martin.craig@eng.ox.ac.uk",
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            "Development Status :: 3 - Alpha",
            "Intended Audience :: Science/Research",
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            "Programming Language :: Python :: 2.7",
            "Programming Language :: Python :: 3",
            "Topic :: Scientific/Engineering :: Bio-Informatics"
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        "description": "# ENABLE - ENhancement of Automated Blood fLow Estimates \n\nENABLE is a technique to evaulate image quality in multi-PLD ASL data. \n\n*Shirzadi et al, \"Enhancement of Automated Blood Flow Estimates (ENABLE) From\nArterial Spin-Labelled MRI\" J Magn Reson Imaging. 2017 Jul 6. doi: 10.1002/jmri.25807*\n\nENABLE performs the following steps:\n\n1. A **preprocessing** step, consisting of tag/control differencing, brain \nextraction, T1 co-registration and segmentation\n\n2. A **sorting** step in which quality measures are calculated for each \nPLD image, namely:\n  - Contrast:Noise ratio in GM (CNR)\n  - Detectibility metric (DETECT, proportion of voxels with significantly greater than zero signal in GM)\n  - Coefficient of variation of difference data (COV, spatial standard deviation divided by spatial mean in GM)\n  - Temporal SNR (TSNR, spatial mean of ASL image divided by temporal STD image in GM)\n\n3. A **selection** step in which a combined quality measure is calculated and the best image is identified:\n  - 0.1*CNR + 1.8*DETECT - COV - TSNR\n \n4. A *CBF generation* step in which a CBF image is generated from the best image\n\n## Usage\n\n    oxasl_enable -i <ASL input file> -t1 <T1 image> -n <Noise ROI image> -o <Output dir>\n\noxasl_enable can also be used as a plug-in for the OXASL ASL processing pipeline - see documentation\nfor this tool at:\n\nhttps://oxasl.readthedocs.io/\n\n### Options\n\n    --version      show program's version number and exit\n    -h, --help     show this help message and exit\n    -i INFILE      ASL data file\n    --t1=T1        T1 map\n    -n NOISE       Noise ROI\n    -o OUTPUT      Output dir\n    --debug=DEBUG  Debug mode",
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        "license": "License granted by University of Oxford for use by academics carrying out research and not for use by consumers or commercial businesses. See LICENSE file for more details",
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        "name": "oxasl-enable",
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        "summary": "Python implementation of the ENABLE quality-based volume selection algorithm for ASL-MRI data",
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