{ "info": { "author": "Will Bradshaw, Arian Sajina and Dario Valenzano", "author_email": "wbradshaw@age.mpg.de, asajina@age.mpg.de, Dario.Valenzano@age.mpg.de", "bugtrack_url": null, "classifiers": [], "description": "# AEGIS\n> Ageing of Evolving Genomes In Silico\n\nA highly versatile discrete numerical model of genome evolution - both sexual and asexual - for a population of agents whose fitness parameters are encoded age-specifically in bit arrays which are free to evolve due to mutation and recombination.\n\nThis is a software implementation of the model described in this [article](https://www.biorxiv.org/content/early/2016/01/26/037952) in section \"The Model\".\n\n## Who uses AEGIS?\n* [Valenzano Lab](http://valenzano-lab.age.mpg.de/)\n\n## Features\nAEGIS can:\n* simulate genome evolution in age-structured populations under a variety of evolutionary constraints\n* simulate both asexually and sexually reproducing populations\n* output simulation objects using [pickle](https://docs.python.org/2/library/pickle.html)\n* output recorded statistics to a [csv](https://en.wikipedia.org/wiki/Comma-separated_values)\n* generate figures from recorded statistics\n* run a simulation until the population has reached evolutionary equilibrium (i.e. the genetic constitution is not expected to change anymore)\n\n## Installation\nSince aegis has dependencies, you might want to put the installation in an isolated Python environment with [virtualenv](https://virtualenv.pypa.io/en/stable/).\nTo install just do:\n```shell\npip install mpi-age-aegis\n```\n\n## Usage\nA detailed usage tutorial with examples is provided on our [GitHub page](https://github.com/valenzano-lab/aegis).\n\n## Related articles\n* [An In Silico Model to Simulate the Evolution of Biological Aging](https://www.biorxiv.org/content/early/2016/01/26/037952)\n\n## Team\n* **Arian \u0160ajina** (Arian.Sajina@age.mpg.de)\n* **William Bradshaw** (William.Bradshaw@age.mpg.de)\n* **Dario Valenzano** (Dario.Valenzano@age.mpg.de)\n\n## Licensing\nThis project is licensed under MIT license.\n\n## Acknowledgments\nThis project is developed in the [Valenzano Lab](http://valenzano-lab.age.mpg.de) of\nthe [Max Planck Institute for Biology of Ageing, Cologne](https://www.age.mpg.de).\nWe thank all the lab members and friends of the lab for their constructive\ncomments and suggestions.\n\n\n", "description_content_type": "text/markdown", "docs_url": null, "download_url": "", "downloads": { "last_day": -1, "last_month": -1, "last_week": -1 }, "home_page": "https://github.com/valenzano-lab/aegis", "keywords": "", "license": "MIT", "maintainer": "", "maintainer_email": "", "name": "mpi-age-aegis", "package_url": "https://pypi.org/project/mpi-age-aegis/", "platform": "", "project_url": "https://pypi.org/project/mpi-age-aegis/", "project_urls": { "Homepage": "https://github.com/valenzano-lab/aegis" }, "release_url": "https://pypi.org/project/mpi-age-aegis/1.0/", "requires_dist": [ "numpy (>=1.15.4)", "scipy (>=1.1.0)", "python-dateutil (>=2.7.5)", "pandas (>=0.23.4)", "matplotlib (==2.1.0)", "seaborn (>=0.9.0)", "pytest (>=4.3.0)" ], "requires_python": "", "summary": "AEGIS - 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