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        "author": "Brandon Reyes",
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        "description": "=========\nCRNT4SBML\n=========\n\n\n.. image:: https://img.shields.io/pypi/v/crnt4sbml.svg\n        :target: https://pypi.python.org/pypi/crnt4sbml\n\n.. image:: https://img.shields.io/travis/PNNL-Comp-Mass-Spec/CRNT4SBML.svg\n        :target: https://travis-ci.org/PNNL-Comp-Mass-Spec/CRNT4SBML\n\n.. image:: https://readthedocs.org/projects/crnt4sbml/badge/?version=latest\n        :target: https://crnt4sbml.readthedocs.io/en/latest/?badge=latest\n        :alt: Documentation Status\n\nCRNT4SBML is an easily installable Python based package available on MacOS and Windows. CRNT4SBML is concentrated on\nproviding a simple workflow for the testing of core CRNT methods directed at detecting bistability in cell signaling\npathways endowed with mass action kinetics.\n\n* Free software: Apache Software License 2.0\n* Documentation: https://crnt4sbml.readthedocs.io.\n\n\nFeatures\n--------\n\n* Routine for testing of the Deficiency Zero and One Theorems.\n* Routine for running the mass conservation approach.\n* Routine for running the semi-diffusive approach.\n\nCiting CRNT4SBML\n-----------------\n\nIf you use CRNT4SBML in your research, we would appreciate it if you use the following citation in any works you publish:\n\n    Brandon C Reyes, Irene Otero-Muras, Michael T Shuen, Alexandre M Tartakovsky, Vladislav A Petyuk,\n    `CRNT4SBML: a Python package for the detection of bistability in biochemical reaction networks <https://academic.oup.com/bioinformatics/advance-article/doi/10.1093/bioinformatics/btaa241/5820009?searchresult=1>`_,\n    Bioinformatics.\n\nCredits\n-------\n\nThis package was created with Cookiecutter_ and the `audreyr/cookiecutter-pypackage`_ project template.\n\n.. _Cookiecutter: https://github.com/audreyr/cookiecutter\n.. _`audreyr/cookiecutter-pypackage`: https://github.com/audreyr/cookiecutter-pypackage\n\n\n=======\nHistory\n=======\n\n0.0.1 (08-22-2019)\n------------------\n\n* First release on PyPI.\n\n0.0.2 (08-23-2019)\n------------------\n\n* Addition of Cytoscape functionality.\n\n0.0.3 (08-26-2019)\n------------------\n\n* Improvements to the plots produced by the continuity analysis.\n\n0.0.4 (09-5-2019)\n------------------\n\n* Addition of safety precautions for numerical continuation.\n\n0.0.5 (09-16-2019)\n------------------\n\n* Addition of routines to parse catalysis in SBML.\n* Addition of routines to automatically generate physiological bounds.\n\n0.0.6 (09-23-2019)\n------------------\n\n* Updating safety wrapper to smoothly work on Windows and Mac.\n\n0.0.7 (10-11-2019)\n------------------\n\n* Adding output to continuity routine to make post-processing simpler.\n\n0.0.8 (10-23-2019)\n------------------\n\n* Adding functionality to allow use of Jupyter notebooks.\n\n0.0.9 (11-6-2019)\n------------------\n\n* Improving stability when creating the equilibrium manifold in the mass conservation approach.\n\n0.0.10 (11-6-2019)\n------------------\n\n* Adding routine for an exhaustive equilibrium manifold creation in the mass conservation approach.\n\n0.0.11 (4-23-2020)\n------------------\n\n* Adding a general approach for mass conserving systems.\n\n0.0.12 (5-21-2020)\n------------------\n\n* Adding a different layout for installation of package.\n\n0.0.13 (8-10-2020)\n------------------\n\n* Improving usability on Windows machines.\n\n0.0.14 (1-28-2021)\n------------------\n\n* Improving the output of plots produced by direct simulation.\n\n0.0.15 (8-25-2021)\n------------------\n\n* Updated tolerances for Bayesian stopping rule to 0.1.\n\n\n",
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